Retired FBI profiler Lyle Barnes is falling apart mentally. Psychologist and trauma expert Daniel Rinaldi thinks he can help Barnes through his terrible night visions. Barnes, however, is also the target of an unknown assassin whose mounting list of victims paralyzes the city and lands Lyle in protective custody. Then Barnes disappears, drawing Daniel and the joint FBI-Pittsburgh PD Task Force into a desperate manhunt. Meanwhile, the mother of a youthful confessed killer awaiting trial is convinced that her son is innocent and appeals to Daniel for help. Against his better judgment, he becomes involved, and soon suspects that much about the case is not as it appears. Can Daniel and the law officials find the missing Barnes before the killer does? Are these two seemingly unconnected cases somehow linked?